carbonic anhydrase inhibitor
- carbonic anhydrase inhibitor
- any of a group of agents that inhibit activity of carbonic anhydrase (carbonate dehydratase). In the kidney this decreases hydrogen ion concentration in the renal tubule, resulting in increased excretion of bicarbonate, sodium, potassium, and water; in the eye it depresses production of aqueous humor and lowers intraocular pressure. These were originally used as diuretics but were replaced by other agents because their diuretic effect is self-limiting; now they are used chiefly for treatment of glaucoma, and also for epilepsy, familial periodic paralysis, acute mountain sickness, and uric acid calculi.
Medical dictionary.
2011.
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carbonic anhydrase inhibitor — any one of a class of drugs that act by blocking the action of the enzyme carbonic anhydrase. This enzyme greatly speeds up the reaction between carbon dioxide and water to form carbonic acid, a compound needed for the production of many of the… … Medical dictionary
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