- uncompetitive inhibition
- inhibition of an enzyme by a substance that binds reversibly to the enzyme-substrate complex. The enzyme-substrate-inhibitor complex cannot yield the normal product until the inhibitor is released.
Medical dictionary. 2011.
uncompetitive inhibition
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Uncompetitive inhibitor — Uncompetitive inhibition takes place when an enzyme inhibitor binds only to the complex formed between the enzyme and the substrate (the E S complex).MechanismThis reduction in the effective concentration of the E S complex increases the enzyme s … Wikipedia
inhibition — 1. Depression or arrest of a function. SEE ALSO: inhibitor. 2. In psychoanalysis, the restraining of instinctual or unconscious drives or tendencies, especially if they conflict with one s conscience or with societal demands. 3. In psychology, a… … Medical dictionary
Mixed inhibition — refers to a combination of two different types of reversible enzyme inhibition – competitive inhibition and uncompetitive inhibition. The term mixed is used when the inhibitor can bind to either the free enzyme or the enzyme substrate complex. In … Wikipedia
Non-competitive inhibition — is a type of enzyme inhibition where the inhibitor reduces the activity of the enzyme, by binding not to the active site on the enzyme, but to a different site.[1] More specifically, it is a special instance of mixed inhibition where the… … Wikipedia
Competitive inhibition — is a form of enzyme inhibition where binding of the inhibitor to the active site on the enzyme prevents binding of the substrate and vice versa. Contents 1 Mechanism 2 Equation 3 Derivation 4 … Wikipedia
Suicide inhibition — Suicide inhibition, also known as suicide inactivation or mechanism based inhibition, is a form of irreversible enzyme inhibition that occurs when an enzyme binds a substrate analogue and forms an irreversible complex with it through a covalent… … Wikipedia
mixed inhibition — noun When components of different inhibition types (competitive, non competitive, uncompetitive) occur at the same time … Wiktionary
Enzyme inhibitor — Enzyme inhibitors are molecules that bind to enzymes and decrease their activity. Since blocking an enzyme s activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. They are also used as herbicides and… … Wikipedia
Enzyme — Biocatalyst redirects here. For the use of natural catalysts in organic chemistry, see Biocatalysis. Human glyoxalase I. Two zinc ions that are needed for the enzyme to catalyze its reaction are shown as purp … Wikipedia
Lineweaver–Burk plot — In biochemistry, the Lineweaver–Burk plot (or double reciprocal plot) is a graphical representation of the Lineweaver–Burk equation of enzyme kinetics, described by Hans Lineweaver and Dean Burk in 1934.[1] Contents 1 … Wikipedia
