slot blot hybridization

slot blot hybridization
a variation on a dot blot hybridization with substitution of a slotted template for the usual one with circular holes; it increases sample capacity and maintains precision.

Medical dictionary. 2011.

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  • slot blot — A dot blot in which samples are placed on a membrane through a series of rectangular slots in a template. This is slightly advantageous because hybridization artefacts are usually circular …   Dictionary of molecular biology

  • Blot (biology) — In molecular biology and genetics, a blot is a method of transferring proteins, DNA or RNA, onto a carrier (for example, a nitrocellulose PVDF or nylon membrane). In many instances, this is done after a gel electrophoresis, transferring the… …   Wikipedia

  • List of molecular biology topics — This is a list of topics in molecular biology. See also list of biochemistry topics. NOTOC # 3 end 3 flanking region 5 end 5 flanking region 5 ribose 3 A acrylamide gels adenine adenosine deaminase deficiency adenovirus agarose gel… …   Wikipedia

  • Nuclear run-on — A nuclear run on assay is conducted to identify the genes that are being transcribed at a certain time. Cell nuclei are isolated rapidly, and incubated with labelled nucleotides and the results are hybridized to a slot blot, which is then exposed …   Wikipedia

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