Langerhans cell histiocytosis multifocal
- Langerhans cell histiocytosis multifocal
- Langerhans cell histiocytosis occurring as erosive accumulations of proliferating Langerhans cells, commonly within the medullary cavities of bones, but also affecting the skin, gingiva, lungs, and stomach. It most commonly affects children and is accompanied by seborrheic eruptions, fever, frequent occurrences of otitis media, mastoiditis, and upper respiratory tract infection, often with lymphadenopathy and splenomegaly. When the triad of calvarial bone defects, exophthalmos, and diabetes insipidus is present, it is referred to as Hand-SchÑŒller-Christian disease.
Medical dictionary.
2011.
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