glycosylceramidase

glycosylceramidase
gly·co·syl·cer·am·i·dase (gli″ko-sil″sə-ramґĭ-dās) [EC 3.2.1.62] an enzyme of the hydrolase class that catalyzes the cleavage of a β-linked sugar residue from β-glycosides with large hydrophobic aglycons, such as galactosyl- and glycosylceramides and phlorizin. Such enzyme activity occurs as part of the β-glycosidase complex (q.v.), along with lactase, in the intestinal brush border membrane, where it is frequently referred to as phlorhizin hydrolase. In this context, it is sometimes described as a composite of glucosylceramidase [EC 3.2.1.45] and galactosylceramidase [EC 3.2.1.46] activities and denoted glycosylceramidase [EC 3.2.1.45–6].

Medical dictionary. 2011.

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