glycoprotein Mac-1

glycoprotein Mac-1
a β2 integrin (CD11b/CD18) expressed on monocytes, macrophages, neutrophils, and NK cells that mediates leukocyte adhesion and serves as a receptor for inactivated complement fragment C3b (iC3b) and for some carbohydrates of certain bacteria and yeasts; it also plays a role in antibody-dependent cellular cytotoxicity. It comprises an α and a β chain; the latter is common also to CR4. Called also Mac-1 and complement receptor 3 (CR3).

Medical dictionary. 2011.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Mac-1 — see under glycoprotein …   Medical dictionary

  • CR3 — glycoprotein Mac 1 …   Medical dictionary

  • CR3 — complement receptor type 3; see glycoprotein Mac 1, under glycoprotein …   Medical dictionary

  • intercellular adhesion molecule 1 — (ICAM 1) a type of cell adhesion molecule that contains five immunoglobulin like domains and is expressed on a variety of cells, including B and T lymphocytes, fibroblasts, keratinocytes, and endothelial cells. It functions as a ligand for… …   Medical dictionary

  • LGALS3BP — Lectin, galactoside binding, soluble, 3 binding protein, also known as LGALS3BP, is a human gene.cite web | title = Entrez Gene: LGALS3BP lectin, galactoside binding, soluble, 3 binding protein| url =… …   Wikipedia

  • CD18 — Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) PDB rendering based on 1l3y …   Wikipedia

  • Pascal Goldschmidt — Pascal J. Goldschmidt Clermont, M.D., is a Belgian born, American cardiologist, and is the Senior Vice President for Medical Affairs and the Dean of the Miller School of Medicine at the University of Miami. He was previously the Edward S. Orgain… …   Wikipedia

  • Macrophage-1 antigen — (or integrin alphaMbeta2) is a complement receptor ( CR3 ) consisting of CD11b and CD18.[1] It binds to C3b and C4b. Contents 1 Function 2 Synonyms and abbreviations 3 …   Wikipedia

  • CD11c — CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a human gene.cite web | title = Entrez Gene: ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)| url =… …   Wikipedia

  • Lipoprotein(a) — (also called Lp(a)) is a lipoprotein subclass. Studies have identified Lp(a) as a putative risk factor for atherosclerotic diseases such as coronary heart disease and stroke.cite journal | author = Danesh J, Collins R, Peto R | title =… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”