glycoprotein IIb/IIIa

glycoprotein IIb/IIIa
a transmembrane protein of platelets; it is an integrin that binds fibrinogen, von Willebrand factor, and other adhesive ligands and plays a role in platelet aggregation and thrombus formation.

Medical dictionary. 2011.

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  • Glycoprotein IIb/IIIa — protein Name = integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) caption = width = HGNCid = 6138 Symbol = ITGA2B AltSymbols = GP2B EntrezGene = 3674 OMIM = 607759 RefSeq = NM 000419 UniProt = P08514 PDB = ECnumber …   Wikipedia

  • Glycoprotein IIb/IIIa inhibitors — In medicine, glycoprotein IIb/IIIa inhibitors, also GpIIb/IIIa inhibitors, is a class of antiplatelet agents. Several GpIIb/IIIa inhibitors exist: *abciximab (ReoPro) *eptifibatide (Integrilin) *tirofiban (Aggrastat)UseGlycoprotein IIb/IIIa… …   Wikipedia

  • Glycoprotein — Not to be confused with peptidoglycan or proteoglycan. N linked protein glycosylation (N glycosylation of N glycans) at Asn residues (Asn x Ser/Thr motifs) in glycoproteins.[1] Glycoproteins are proteins that contain oligosaccharide chai …   Wikipedia

  • Интегрин альфа-IIb — Структура белка ITGA2B Обоз …   Википедия

  • Pascal Goldschmidt — Pascal J. Goldschmidt Clermont, M.D., is a Belgian born, American cardiologist, and is the Senior Vice President for Medical Affairs and the Dean of the Miller School of Medicine at the University of Miami. He was previously the Edward S. Orgain… …   Wikipedia

  • Coagulation — This article is about blood clotting. For other meanings see Coagulation (disambiguation). Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis, the cessation of blood loss from a damaged vessel,… …   Wikipedia

  • ITGA2B — Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), also known as ITGA2B, is a human gene. PBB Summary section title = summary text = ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral… …   Wikipedia

  • CD61 — Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), also known as ITGB3, is a human gene. CD61 is a cluster of differentiation found on thrombocytes. PBB Summary section title = summary text = The ITGB3 protein product is the integrin… …   Wikipedia

  • Abciximab — drugbox mab source = chimeric/human target = CD41 7E3 CAS number = 143653 53 6 ATC prefix = B01 ATC suffix = AC13 ATC supplemental = PubChem = DrugBank = BTD00041 C=6462 | H=9964 | N=1690 | O=2049 | S=48 molecular weight = 145651.1 g/mol… …   Wikipedia

  • Eptifibatide — drugbox IUPAC name = N 6 (aminoiminomethyl) N 2 (3 mercapto 1 oxopropyl L lysylglycyl L a aspartyl L tryptophyl L prolyl L cysteinamide width = 400 CAS number = 188627 80 7 ATC prefix = B01 ATC suffix = AC16 ATC supplemental = PubChem = 123610… …   Wikipedia

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