glycine hydroxymethyltransferase

glycine hydroxymethyltransferase
gly·cine hy·droxy·meth·yl·trans·fer·ase (gliґsēn hi-drok″se-meth″əl-transґfər-ās) [EC 2.1.2.1] an enzyme of the transferase class that catalyzes the reversible transfer of a methylene group from serine to tetrahydrofolate to form 5,10-methylenetetrahydrofolate and glycine. The enzyme is a pyridoxal phosphate protein. The reaction occurs in mitochondria and is a major source of one-carbon units for folate-mediated transfer reactions. Called also serine hydroxymethyltransferase.

Medical dictionary. 2011.

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  • Glycine hydroxymethyltransferase — In enzymology, a glycine hydroxymethyltransferase (EC number|2.1.2.1) is an enzyme that catalyzes the chemical reaction:5,10 methylenetetrahydrofolate + glycine + H2O ightleftharpoons tetrahydrofolate + L serineThe 3 substrates of this enzyme are …   Wikipedia

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  • serine hydroxymethyltransferase — ser·ine hy·droxy·meth·yl·trans·fer·ase (sērґēn hi drok″se meth″əl transґfər ās) glycine hydroxymethyltransferase …   Medical dictionary

  • Serine hydroxymethyltransferase — protein Name=serine hydroxymethyltransferase 1 (soluble) caption= width= HGNCid=10850 Symbol=SHMT1 AltSymbols= EntrezGene=6470 OMIM=182144 RefSeq=NM 148918 UniProt=P34896 PDB= ECnumber= Chromosome=17 Arm=p Band=11.2 LocusSupplementaryData=protein …   Wikipedia

  • List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… …   Wikipedia

  • Methionine synthase — 5 methyltetrahydrofolate homocysteine methyltransferase PDB rendering based on 2o2k …   Wikipedia

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  • Metabolism — Cell metabolism redirects here. For the journal, see Cell Metabolism. Structure of adenosine triphosphate, a central intermediate in energy metabolism Metabolism (from Greek: μεταβολή metabolē , change or Greek: μεταβολισμός metabolismos,… …   Wikipedia

  • Amino acid — This article is about the class of chemicals. For the structures and properties of the standard proteinogenic amino acids, see Proteinogenic amino acid. The generic structure of an alpha amino acid in its unionized form …   Wikipedia

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