glucan 14-α-glucosidase

glu·can 1,4-α-glu·co·si·dase (glooґkan gloo-koґsĭ-dās) [EC 3.2.1.3] a lysosomal enzyme of the hydrolase class that catalyzes the cleavage of glucose residues from polyglucoside chains by hydrolyzing terminal α-1,4 or α-1,6 bonds; the enzyme degrades glycogen to glucose in the lysosomes. Deficiency or absence of enzyme activity, an autosomal recessive trait, results in glycogen storage disease, type II. Called also acid maltase and lysosomal α-glucosidase.