intercapillary glomerulosclerosis

intercapillary glomerulosclerosis
a degenerative complication of diabetes mellitus in which there is glomerular mesangial expansion with either diffuse or nodular lesions; the nodular lesions are known as Kimmelstiel-Wilson lesions. Symptoms include albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy. Called also diabetic g. The type with nodular lesions is also called Kimmelstiel-Wilson syndrome.

Medical dictionary. 2011.

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  • glomerulosclerosis — Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes. SYN: glomerular sclerosis. [glomerulus + G. sklerosis, hardness] …   Medical dictionary

  • diabetic glomerulosclerosis — the characteristic microscopic changes seen in a diabetic kidney after many years of progressive damage. * * * intercapillary g …   Medical dictionary

  • diabetic glomerulopathy — intercapillary glomerulosclerosis …   Medical dictionary

  • Kimmelstiel-Wilson syndrome — Diabetic nephropathy (kidney disease). Kimmelstiel Wilson syndrome is a kidney condition associated with long standing diabetes. It affects the network of tiny blood vessels (the microvasculature) in the glomerulus, a key structure in the kidney… …   Medical dictionary

  • Kimmelstiel-Wilson lesion (nodule) syndrome — Kim·mel·stiel Wil·son lesion (nodule), syndrome (kimґəl stēl wilґsən) [Paul Kimmelstiel, German pathologist in the United States, 1900–1970; Clifford Wilson, British physician, 1906–1997] see under lesion and see intercapillary …   Medical dictionary

  • Kimmelstiel-Wilson lesion — a microscopic spherical hyaline mass surrounded by capillaries, found in the kidney glomerulus in the nodular form of intercapillary glomerulosclerosis and virtually pathognomonic of diabetes mellitus. Called also Kimmelstiel Wilson nodule …   Medical dictionary

  • Diabetic nephropathy — Classification and external resources Photomicrography of nodular glomerulosclerosis in Kimmelstein Wilson syndrome. Source: CDC ICD 10 E10.2, E11.2, E12.2, E13.2, E …   Wikipedia

  • arteriolar nephrosclerosis — nephrosclerosis of arterioles; it usually has an insidious onset and is often associated with hypertension, cylindruria, edema, hypertrophy of the heart, degeneration of renal tubules, and glomerulonephritis, resulting in renal insufficiency,… …   Medical dictionary

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