germline

germline
germ·line (jərmґlīn) the sequence of cells in the line of direct descent from zygote to gamete, as opposed to somatic cells (all other body cells). Mutations in germline cells are transmitted to progeny; those in somatic cells are not. Written also germ line.

Medical dictionary. 2011.

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  • Germline — In biology and genetics, the germline of a mature or developing individual is the line (sequence) of germ cells that have genetic material that may be passed to a child.For example, sex cells such as the sperm or the egg, are part of the germline …   Wikipedia

  • Germline Mosaicism — Germline mosaicism, also known as gonadal mosaicism, is a condition in which the precursor (germline) cells to ova and spermatazoa are a mixture of two or more genetically different cell lines.External Link… …   Wikipedia

  • Germline mutation — A germline mutation is any detectable and heritable variation in the lineage of germ cells. Mutations in these cells are transmitted to offspring, while, on the other hand, those in somatic cells are not. A germline mutation gives rise to a… …   Wikipedia

  • Germline mutation — A heritable change in the DNA that occurred in a germ cell (a cell destined to become an egg or in the sperm) or the zygote (the conceptus) at the single cell stage. When transmitted to a child, a germline mutation is incorporated in every cell… …   Medical dictionary

  • germline mutation — A gene change in the body s reproductive cells (egg or sperm) that becomes incorporated into the DNA of every cell in the body of offspring; germline mutations are passed on from parents to offspring. Also called hereditary mutation …   English dictionary of cancer terms

  • germline — noun those cells of an individual that have genetic material that could be passed to offspring; the source of gametes …   Wiktionary

  • germline insertion — /jerrm luyn /, Biotech. the insertion of cloned genes into the egg or sperm cell of an organism, using a gene transfer technique, in order to perpetuate a desired trait in its descendants, as pest resistance in a crop plant. * * * …   Universalium

  • germline insertion — /jerrm luyn /, Biotech. the insertion of cloned genes into the egg or sperm cell of an organism, using a gene transfer technique, in order to perpetuate a desired trait in its descendants, as pest resistance in a crop plant …   Useful english dictionary

  • Mutation, germline — A heritable change in the DNA that occurred in a germ cell (a cell destined to become an egg or in the sperm) or the zygote (the conceptus) at the single cell stage. When transmitted to a child, a germline mutation is incorporated in every cell… …   Medical dictionary

  • recombinational germline theory — a theory of the origin of antibody diversity, according to which the DNA coding for a single immunoglobulin chain is assembled by a somatic recombinational event from two genes, one a unique constant region gene and the other one of several… …   Medical dictionary

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