Mismatch repair cancer syndrome — Classification and external resources OMIM 276300 DiseasesDB 29793 eMedicine … Wikipedia
DNA mismatch repair — is a system for recognizing and repairing erroneous insertion, deletion and mis incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage.[1][2] Mismatch repair is strand… … Wikipedia
Gene conversion — is an event in DNA genetic recombination, which occurs at high frequencies during meiotic division but which also occurs in somatic cells. It is a process by which DNA sequence information is transferred from one DNA helix (which remains… … Wikipedia
gene conversion — A phenomenon in which alleles are segregated in a 3:1 not 2:2 ratio in meiosis. May be a result of DNA polymerase switching templates and copying from the other homologous sequence, or a result of mismatch repair (nucleotides being removed from… … Dictionary of molecular biology
DNA repair — For the journal, see DNA Repair (journal). DNA damage resulting in multiple broken chromosomes DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human… … Wikipedia
DNA repair-deficiency disorder — Classification and external resources MeSH D049914 A DNA repair deficiency disorder is a medical condition due to reduced functionality of DNA repair. DNA repair defects are seen in nearly all of the diseases described as accelerated aging… … Wikipedia
Caretaker gene — Changes in the genome that allow uncontrolled cell proliferation or cell immortality are responsible for cancer. It is believed that the major changes in the genome that lead to cancer arise from mutations in Tumor Suppressor Genes 1. In 1997,… … Wikipedia
Postreplication repair — is the repair of damage to the DNA that takes place after replication. Some example genes in humans include: BRCA2 and BRCA1 BLM NBS1 DNA damage prevents the normal enzymatic synthesis of DNA by the replication fork.[1][2][3][4] … Wikipedia
Excision repair — is a term applied to several DNA repair mechanisms.Excision repair mechanisms that remove the damaged nucleotide replacing it with an undamaged nucleotide complementary to the nucleotide in the undamaged DNA strand. These include: *Base excision… … Wikipedia
Hereditary nonpolyposis colorectal cancer — Classification and external resources ICD 10 C18 C20 ICD 9 … Wikipedia