immunoglobulin genes

immunoglobulin genes
the genes coding for immunoglobulin heavy and light chains, which are organized in three loci coding for κ light chains, λ light chains, and heavy chains found on human chromosomes 2, 22, and 14, respectively. These genes undergo several DNA rearrangements during the differentiation of stem cells into B cells and plasma cells, permitting synthesis of the various immunoglobulin classes.

Medical dictionary. 2011.

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  • immunoglobulin genes — immunoglobulin genes. См. гены иммуноглобулинов. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

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  • Immunoglobulin light chain — Schematic diagram of an typical antibody showing two Ig heavy chains (blue) linked by disulfide bonds to two Ig light chains (green). The constant (C) and variable (V) domains are shown …   Wikipedia

  • Kappachain immunoglobulin — The κ (Kappa) chain is one of the immunoglobulin light chain polypeptide isotypes [Male, D., Brostoff, J., Roth, D.B., Roitt, I. 2006. Immunology. 7th ed., Canada: Elsevier Limited] . The other main type is the λ (Lamda) light chain. Both κ and λ …   Wikipedia

  • Complement receptor of the immunoglobulin family — V set and immunoglobulin domain containing 4 Identifiers Symbol VSIG4 Entrez 11326 HUGO …   Wikipedia

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  • Killer cell immunoglobulin-like receptor — (also called killer inhibitor receptor Lippincott s Illustrated Reviews: Immunology. Paperback: 384 pages. Publisher: Lippincott Williams Wilkins; (July 1, 2007). Language: English. ISBN 10: 0781795435. ISBN 13: 978 0781795432. Page 20 ] is a… …   Wikipedia

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  • Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… …   Wikipedia

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