ascertainment

ascertainment
In epidemiological and genetic research, the method by which a person, pedigree, or cluster is brought to the attention of an investigator; has a bearing on the interpretation of segregation ratios, concordance rates, linkage analysis, and other probability features.
- complete a. method by which all families with at least one affected individual in a population are certain or have an equal chance of being identified by survey or an appropriate random sampling technique.
- incomplete a. method of locating affected individuals in which probability of locating any specific patient has a known value between 0 and 1. SYN: truncate a..
- single a. method of a. of locating affected individuals by hospital or clinic admission or another way in which probability of encountering the same family twice approaches zero; thus, the probability that a family will be ascertained is proportional to the number of affected members.
- total a. method by which all members of a population at risk of a trait are discerned or equally likely to be contained in a sample thereof.
- truncate a. SYN: incomplete a..

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as·cer·tain·ment (ă″sər-tānґmənt) in genetic studies, the method by which persons with a trait or disease are selected or found by an investigator.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Ascertainment — As cer*tain ment, n. The act of ascertaining; a reducing to certainty; a finding out by investigation; discovery. [1913 Webster] The positive ascertainment of its limits. Burke. [1913 Webster] …   The Collaborative International Dictionary of English

  • ascertainment — index analysis, certification (certainness), collation, conclusion (determination), detection, determination …   Law dictionary

  • ascertainment — ˌ ̷ ̷ ̷ ̷ˈ ̷ ̷mənt noun ( s) : the act of ascertaining: a. archaic : a reducing to certainty : exact determination that a period might be put and some ascertainment made and a time fixed Oliver Cromwell b …   Useful english dictionary

  • ascertainment — ascertain ► VERB ▪ find out for certain. DERIVATIVES ascertainable adjective ascertainment noun. ORIGIN Old French acertener, from Latin certus settled, sure …   English terms dictionary

  • Ascertainment bias — In scientific research, ascertainment bias occurs when false results are produced by non random sampling and conclusions made about an entire group are based on a distorted or nontypical sample. If this is not accounted for, results can be… …   Wikipedia

  • ascertainment — noun see ascertain …   New Collegiate Dictionary

  • ascertainment — See ascertainable. * * * …   Universalium

  • ascertainment — noun The act of ascertaining …   Wiktionary

  • ascertainment — (Roget s Thesaurus II) noun Something that has been discovered: discovery, find, finding, strike. See TEACH …   English dictionary for students

  • ascertainment — as·cer tain·ment || ‚æsÉ™(r) teɪnmÉ™nt n. act of making certain, finding out, verification …   English contemporary dictionary

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