familial Mediterranean fever

familial Mediterranean fever
an autoinflammatory disease (q.v.) of autosomal recessive inheritance, usually occurring in Armenians and Sephardic Jews, caused by mutation of the MEFV gene (locus: 16p13), which encodes pyrin. It is characterized by short recurrent attacks of fever with pain in the abdomen, chest, or joints and erythema resembling that seen in erysipelas; it is sometimes complicated by AA amyloidosis (q.v.). Called also benign paroxysmal peritonitis, periodic peritonitis, familial recurrent polyserositis, and periodic or recurrent polyserositis.

Medical dictionary. 2011.

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  • Familial Mediterranean fever — Classification and external resources ICD 10 E85.0 ICD 9 277.31 …   Wikipedia

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