bacterial dissociation

bacterial dissociation
the change, due to mutation and selection, in colonial morphology (usually from mucoid or smooth to rough) of bacteria in culture on laboratory media; called also microbic d. See also smooth-rough variation, under variation.

Medical dictionary. 2011.

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  • smooth-rough variation — S R variation a genetic mutation or an adaptation seen in bacteria, most often evidenced by a change in the surface of colonies from smooth (S, glossy) to rough (R, dull). The change correlates with pathogenicity, S strains being generally more… …   Medical dictionary

  • R strain — rough strain a type of strain that results from bacterial dissociation; rough or R colonies have a dull, uneven surface and irregular border, the growth in fluid media tends to flake out, no capsules are seen, and the culture tends to be less… …   Medical dictionary

  • S strain — smooth strain a type of strain that results from bacterial dissociation; smooth or S colonies have a smooth surface and an unbroken border, growth in fluid media tends to be diffuse; capsules, if present at all, are found in this strain, and the… …   Medical dictionary

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