Rosai-Dorfman disease

Rosai-Dorfman disease
a rare syndrome, seen usually in children or adolescents, in which cervical lymph nodes (and sometimes other lymph nodes) are massively swollen and contain large numbers of histiocytes; extranodal disease is common, sometimes with fever, anemia, neutrophilia, elevated erythrocyte sedimentation rate, and hypergammaglobulinemia. Called also sinus histiocytosis with massive lymphadenopathy.

Medical dictionary. 2011.

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