nuclear pore complex

nuclear pore complex
a nuclear pore (q.v.) and its associated glycoproteins, which regulates transport between the nucleus and the cytoplasm. It has a diameter of approximately 80–100 nm and is composed of three stacked, octagonally symmetric, ringlike arrays of proteins (the cytoplasmic, middle, and nucleoplasmic rings), cytoplasmic fibers, a transporter, and a nuclear basket.

Medical dictionary. 2011.

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  • nuclear pore complex — noun A proteinaceous assembly that selectively transports cargoes across the nuclear envelope …   Wiktionary

  • Nuclear pore — Diagram of human cell nucleus. Nuclear pore labeled at bottom left …   Wikipedia

  • Nuclear localization sequence — A nuclear localization signal or sequence (NLS) is an amino acid sequence which tags a protein for import into the cell nucleus by nuclear transport. Typically, this signal consists of one or more short sequences of positively charged lysines or… …   Wikipedia

  • Nuclear transport — The entry and exit of large molecules from the cell nucleus is tightly controlled by the nuclear pore complexes (NPCs). Although small molecules can enter the nucleus without regulation,[1] macromolecules such as RNA and proteins require… …   Wikipedia

  • Nuclear localization signal — A nuclear localizing sequence (NLS) is an amino acid sequence which acts like a tag on the exposed surface of a protein. This sequence is used to target the protein to the cell nucleus through the Nuclear Pore Complex and to direct a newly… …   Wikipedia

  • Nuclear envelope — Human cell nucleus A nuclear envelope (NE) (also known as the perinuclear envelope, nuclear membrane, nucleolemma or karyotheca) is a double lipid bilayer that encloses the genetic material in eukaryotic cells. The nuclear envelope also serves as …   Wikipedia

  • Nuclear dots — ND10s in human embryonic lung cells Nuclear dots (Aliases: Nuclear bodies , nuclear domains , PML bodies ) are punctate structures found in the nucleus of certain cells. Nuclear bodies (NBs) were first seen as prominent interchromatin structures… …   Wikipedia

  • Nuclear export signal — A nuclear export signal (NES) is a short amino acid sequence of 4 hydrophobic residues in a protein that targets it for export from the cell nucleus to the cytoplasm through the nuclear pore complex using nuclear transport. It has the opposite… …   Wikipedia

  • Pore nucléaire — Les pores nucléaires sont de grands complexes protéiques (poids moléculaire estimé à 125 000 kDa) traversant l enveloppe nucléaire qui est une double membrane entourant le noyau des cellules eucaryotes. Les pores nucléaires permettent les… …   Wikipédia en Français

  • nuclear pores — small octagonal openings in the nuclear envelope at sites where the two nuclear membranes are in contact and through which transport between the nucleus and the cytoplasm occurs; the pore and the associated structures embedded in its rim form the …   Medical dictionary

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