C3bBb

C3bBb
the alternative pathway C3 convertase, which splits C3 into C3a and C3b; it is generated by the interaction of factor B and factor D with C3b deposited on activators of the alternative pathway and thus protected from inactivation by factor I and factor H. It is unstable until the addition of properdin. See also note at complement.

Medical dictionary. 2011.

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