reactive perforating collagenosis
- reactive perforating collagenosis
- (RPC) a rare, usually familial type of acquired perforating dermatosis in which collagen fibers are extruded through the epidermis. It occurs at sites of frequent trauma (e.g., the knees and backs of the hands) and is characterized by skin-colored papules with a central area of umbilication containing keratinous material. Lesions grow to 5–8 mm in diameter and regress spontaneously; the Koebner phenomenon may occur. An acquired form, associated with diabetes and renal insufficiency, also occurs.
Medical dictionary.
2011.
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