Medical dictionary. 2011.
Citrullination — or deimination is the term used for the post translational modification of the amino acid arginine in a protein into the amino acid citrulline. This reaction, shown below, is performed by enzymes called peptidylarginine deiminases (PADs). Note… … Wikipedia
Mutated citrullinated vimentin — Detection of autoantibodies against mutated citrullinated vimentin is part of RA diagnostics (rheumatoid arthritis), especially in sera negative for rheumatoid factor (RF negative sera). Anti MCV antibodies are member of ACPA family, a group of… … Wikipedia
Antikörper gegen citrullinierte Peptide/Proteine — ACPAs oder Antikörper gegen citrullinierte Peptide/Proteine, (engl. Anti citrullinated peptide/protein antibodies, daher kurz: ACPA) sind Autoantikörper (Antikörper gegen Bestandteile des eigenen Körpers), die bei Patienten mit rheumatoider… … Deutsch Wikipedia
Histone — In biology, histones are the chief protein components of chromatin. They act as spools around which DNA winds, and they play a role in gene regulation. Without histones, the unwound DNA in chromosomes would be very long. For example, each human… … Wikipedia
Citrulline — Citrulline … Wikipedia
Posttranslational modification — (PTM) is the chemical modification of a protein after its translation. It is one of the later steps in protein biosynthesis for many proteins.A protein (also called a polypeptide) is a chain of amino acids. During protein synthesis, 20 different… … Wikipedia
Anti-citrullinated protein antibody — Citrulline Anti citrullinated protein antibodies (ACPA) or anti cyclic citrullinated protein antibodies (anti CCP) are autoantibodies (antibodies directed against one or more of an individual’s own proteins) that are frequently detected in the… … Wikipedia
Mutiertes Citrulliniertes Vimentin — Der Nachweis von Autoantikörpern gegen Mutiertes Citrulliniertes Vimentin (MCV) ist ein Laborparameter zur Diagnose der rheumatoiden Arthritis (RA).[1] Bei der RA handelt es sich um eine Autoimmunerkrankung. Der Nachweis bestimmter Autoantikörper … Deutsch Wikipedia
Amino acid — This article is about the class of chemicals. For the structures and properties of the standard proteinogenic amino acids, see Proteinogenic amino acid. The generic structure of an alpha amino acid in its unionized form … Wikipedia
Rheumatoid arthritis — Classification and external resources A hand affected by rheumatoid arthritis ICD 10 M … Wikipedia
