third-generation cephalosporin

third-generation cephalosporin
any of a group of β-lactamase–resistant cephalosporins that are more active against gram-negative organisms but less active against gram-positive organisms than are second-generation agents; it includes cefixime, cefoperazone, cefotaxime, cefpodoxime, ceftazidime, ceftizoxime, and ceftriaxone.

Medical dictionary. 2011.

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  • fourth-generation cephalosporin — a broad spectrum cephalosporin having the greatest activity against gram negative organisms of any of the cephalosporins. Cefepime is often so classified, although it is sometimes included with the third generation cephalosporins …   Medical dictionary

  • Cephalosporin — See also: Discovery and development of cephalosporins Core structure of the cephalosporins …   Wikipedia

  • cephalosporin — /sef euh loh spawr in, spohr /, n. Pharm. any of a group of widely used broad spectrum antibiotics, originally isolated as a product of fermentation from the fungus Cephalosporium acremonium. [1950 55; < NL Cephalospor(ium) the genus (see CEPHALO …   Universalium

  • cephalosporin — n. any one of a group of semisynthetic beta lactam antibiotics, derived from the mould Cephalosporium, which are effective against a wide range of microorganisms and are therefore used in a variety of infections. The older (first generation)… …   The new mediacal dictionary

  • Ceftazidime — Systematic (IUPAC) name (6R,7R,Z) 7 (2 (2 aminothiazol 4 yl) 2 (2 carboxypropan 2 yloxyimino)acetamido) 8 oxo 3 (pyridinium 1 ylmethyl) 5 thia 1 aza bicyclo[4.2.0] oct 2 ene 2 carboxylate …   Wikipedia

  • Cefotaxime — Systematic (IUPAC) name (6R,7R,Z) 3 (acetoxymethyl) 7 (2 (2 aminothiazol 4 yl) 2 (methoxyimino)acetamido) 8 oxo 5 thia 1 azabicyclo[4.2.0] oct 2 ene 2 carboxylic acid …   Wikipedia

  • moxalactam — A third generation cephalosporin with a broad spectrum of antibacterial action; causes bleeding disorders, which limit its use. * * * moxa·lac·tam .mäk sə lak .tam n a cephalosporin antibiotic administered parenterally in the form of its disodium …   Medical dictionary

  • Cefixime — Systematic (IUPAC) name (6R,7R) 7 {[2 (2 amino 1,3 thiazol 4 yl) 2 (carboxy methoxyimino)acetyl]amino} 3 ethenyl 8 oxo 5 thia 1 azabicyclo[4.2.0]oct 2 ene 2 carboxylic acid Clin …   Wikipedia

  • Cefditoren — Systematic (IUPAC) name (7R) 7 ((Z) 2 (2 Aminothiazol 4 yl) 2 (methoxyimino)acetamido) 3 ((Z) 2 (4 methylthiazol 5 yl)vinyl) 8 oxo 5 thia 1 azabicyclo[4.2.0]oct 2 ene 2 carboxylic acid …   Wikipedia

  • Ceftizoxime — Systematic (IUPAC) name (6R,7R) 7 {[(2Z) 2 (2 amino 1,3 thiazol 4 yl) 2 methoxyiminoacetyl]amino] 8 oxo 5 thia 1 azabicyclo[4.2.0]oct 2 ene 2 carboxylic acid Clinical data …   Wikipedia

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