interstitial cells of Cajal
- interstitial cells of Cajal
- (ICCs) pleomorphic cells with oval nuclei and long, branching cytoplasmic processes that interlace to form a network, occurring in the walls of the gastrointestinal tract. They are important in the regulation of gastrointestinal motility, transmitting impulses from enteric neurons to smooth muscle cells and serving as pacemakers. They are grouped into three functional types, each of which occurs in a specific location: in the plane of the myenteric plexus (ICCMY), near the submucosal plexus (ICCSM), and between the circular and longitudinal muscle layers (ICCIM).
Medical dictionary.
2011.
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