helper cells

helper cells
helper T cells differentiated T lymphocytes whose cooperation (help) is required for the production of antibody against most (T-dependent) antigens. Activation of B lymphocytes (B cells) requires recognition of the antigenic determinant against which specific antibody is produced by antigen receptors on a B cell, recognition of some other antigenic determinant by antigen receptors on a helper cell, and a signal passed from the helper cell to the B cell, probably requiring direct cell-to-cell contact. Murine helper cells are marked by the Ly-1 antigen, human helper cells by the CD4 antigen. See also lymphocyte.

Medical dictionary. 2011.

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  • helper cells — helper cells. = TH lymphocytes (см.). (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • helper cells — helper cells. См. Т хелперы. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • T-helper cells — (= TH cells; Th1; Th2) There are now recognized to be two subclasses of CD4 positive T helper cells, Th1 and Th2. Th1 cells produce IL 2, IFN g and TNF a and do not produce IL 4, IL 5 and IL 10. They are associated with cell mediated immunity.… …   Dictionary of molecular biology

  • T-helper cells — helper c s …   Medical dictionary

  • Helper cell — A type of T cell that participates in the immune response by recognizing foreign antigens and secreting substances called cytokines that activate T and B cells. Helper cells fall into two main classes: those that activate other T cells to achieve …   Medical dictionary

  • Helper/suppressor ratio — The T Lymphocyte Helper/Suppressor Profile (Helper/Suppressor ratio, T4:T8 ratio, CD4:CD8 ratio) is a basic laboratory test in which the percentage of CD3 positive lymphocytes in the blood positive for CD4 (T helper cells) and CD8 (a class of… …   Wikipedia

  • helper T-cell — See T helper cells …   Dictionary of molecular biology

  • helper T cell — n. a type of T cell that helps coordinate the immune response, especially by activating B cells: the AIDS virus targets and destroys these T cells …   English World dictionary

  • helper T lymphocytes — helper T cells …   Medical dictionary

  • helper T cell — noun T cell with CD4 receptor that recognizes antigens on the surface of a virus infected cell and secretes lymphokines that stimulate B cells and killer T cells; helper T cells are infected and killed by the AIDS virus • Syn: ↑helper cell, ↑CD4… …   Useful english dictionary

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