foreign body giant cells

foreign body giant cells
giant cells that have clusters of nuclei scattered in an irregular pattern throughout the cytoplasm. They are formed by coalescence and fusion of macrophages, with only a rare internal nuclear division, and are characteristic of inflammation induced by inoculation or implantation of exogenous materials resistant to degradation.

Medical dictionary. 2011.

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  • foreign body reaction — a granulomatous inflammatory reaction evoked by the presence of an exogenous material in the tissues, a characteristic feature of which is the formation of foreign body giant cells …   Medical dictionary

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  • Langhans giant cells — giant cells that resemble foreign body giant cells but have their nuclei arranged in a circle or a horseshoe shaped pattern at the periphery, often seen in granulomatous inflammation …   Medical dictionary

  • Langhans' giant cells — Multinucleate cells formed by fusion of epithelioid macrophages and associated with the central part of early tubercular lesions. Similar to foreign body giant cells, but with the nuclei peripherally located …   Dictionary of molecular biology

  • Giant cell — Multinucleated giant cells due to an infection. H E stain. A giant cell is a mass formed by the union of several distinct cells (usually macrophages).[1] It can arise in response to an infection or foreign body. Types include: foreign body giant… …   Wikipedia

  • giant cell — gi·ant cell jī ənt n an unusually large cell esp a large multinucleate often phagocytic cell (as those characteristic of tubercular lesions, various sarcomas, or the megakaryocytes of the red marrow) * * * any large cell, such as a megakaryocyte …   Medical dictionary

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  • giant cell — ▪ pathology also called  Langhans giant cell        large cell characterized by an arc of nuclei (nucleus) toward the outer membrane. The cell is formed by the fusion of epithelioid cells, which are derived from immune cells called macrophages.… …   Universalium

  • body — 1. The head, neck, trunk, and extremities. The human b., consisting of head (caput), neck (collum), trunk (truncus), and limbs (membra). 2. The material part of a human, as distinguished from the …   Medical dictionary

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