carbamoyl-phosphate synthase (glutamine-hydrolyzing)
- carbamoyl-phosphate synthase (glutamine-hydrolyzing)
- car·bam·o·yl-phos·phate syn·thase (glu·ta·mine-hy·dro·lyz·ing) (kahr-bamґo-əl-fosґfāt sinґthās glooґtə-mēn hiґdro-li-zing) [EC 6.3.5.5] an enzyme activity of the trifunctional CAD protein (q.v.); it is a ligase that catalyzes the formation of carbamoyl phosphate as the first step in the biosynthesis of pyrimidine nucleotides. Glutamine is the nitrogen donor in the reaction, which is cytosolic and is inhibited by UTP.
Medical dictionary.
2011.
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carbamoyl phosphate synthetase — (CPS) car·bam·o·yl phos·phate syn·the·tase (CPS) (kahr bamґo əl fosґfāt sinґthə tās) 1. carbamoyl phosphate synthase (ammonia); called also carbamoyl phosphate synthetase I (CPSI). 2. carbamoyl phosphate synthase (glutamine… … Medical dictionary
CPSII — carbamoyl phosphate synthetase II; see carbamoyl phosphate synthase (glutamine hydrolyzing) … Medical dictionary
CAD protein — a protein containing catalytic sites for three enzyme activities: carbamoyl phosphate synthase (glutamine hydrolyzing) [EC 6.3.5.5], aspartate carbamoyltransferase [EC 2.1.3.2], and dihydroorotase [EC 3.5.2.3]. The enzyme activities catalyze the… … Medical dictionary
