oligoclonal bands

oligoclonal bands
discrete bands of immunoglobulins with decreased electrophoretic mobility; their appearance in electrophoretograms of cerebrospinal fluid when absent in the serum is a sign of possible multiple sclerosis or other diseases of the central nervous system.

Medical dictionary. 2011.

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  • oligoclonal bands — immunoglobulin bands found in the cerebrospinal fluid (CSF) taken at lumbar puncture. Bands isolated only in the CSF and not in the serum indicate local synthesis and are seen in such conditions as multiple sclerosis …   The new mediacal dictionary

  • Oligoclonal band — Oligoclonal bands are bands of immunoglobulins that are seen when a patient s blood serum, gained from blood plasma, or cerebrospinal fluid (CSF) is analyzed. Two methods of analysis are possible: (a) protein electrophoresis, a method of… …   Wikipedia

  • oligoclonal — oli·go·clon·al klōn əl adj 1) cloned or derived from one or a few cells or molecules <oligoclonal T cells> <oligoclonal lymphomas> 2) of, relating to, or being any small group of proteins that migrate close together during… …   Medical dictionary

  • oligoclonal band — noun One of bands of immunoglobulins that are seen when a patients blood plasma or cerebrospinal fluid (CSF) is analyzed …   Wiktionary

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  • McDonald criteria — The McDonald criteria are diagnostic criteria for multiple sclerosis (MS). These criteria are named after neurologist W. Ian McDonald. In April 2001 an international panel in association with the National Multiple Sclerosis Society (NMSS) of… …   Wikipedia

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  • Cerebrospinal fluid — 4 vials of CSF Cerebrospinal fluid (CSF), Liquor cerebrospinalis, is a clear, colorless, salty bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord. In essence, the brain floats …   Wikipedia

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