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al·lo·pu·ri·nol .al-ō-'pyu̇r-ə-.nȯl, -.nōl n a drug C3H4N4O used to promote excretion of uric acid esp. in the treatment of gout

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a drug used in the treatment of chronic gout. It acts by reducing the level of uric acid in tissues and blood. It is administered by mouth; side-effects include nausea, vomiting, diarrhoea, headache, fever, stomach pains, and skin rashes. Occasionally, nerve damage and enlargement of the liver may occur. Trade name: Zyloric.

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al·lo·pur·i·nol (al″o-pūrґĭ-nol) [USP] an isomer of hypoxanthine; used in the treatment of hyperuricemia of gout and the prophylaxis and treatment of that secondary to blood dyscrasias or cancer chemotherapy, for prophylaxis of recurrent formation of uric acid and oxalate renal calculi, and for prophylaxis and treatment of uric acid nephropathy. Both allopurinol and its primary metabolite, oxypurinol, are potent inhibitors of xanthine oxidase and reduce serum levels and urinary excretion of uric acid.

Medical dictionary. 2011.

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  • Allopurinol — Général Nom IUPAC 1,2 dihydro 4H pyrazolo[3,4 d]pyrimidin 4 one No CAS …   Wikipédia en Français

  • Allopurinol — Saltar a navegación, búsqueda Estructura química del allopurinol. Allopurinol es un compuesto químico empleado como medicamento frente a la hiperuricemia (exceso de ácido úrico en plasma sanguíneo) y sus complicaciones, como la gota …   Wikipedia Español

  • allopurinol — ● allopurinol nom masculin Médicament qui inhibe la synthèse de l acide urique dans l organisme. (Il est utilisé dans le traitement de la goutte.) …   Encyclopédie Universelle

  • allopurinol — [al′ō pyoor′ə nôl΄, al′ō pyoor′ənōl΄; al΄əpyoor′ə nôl΄, al΄əpyoor′ə nōl΄] n. a white, powdery drug that is an isomer of hypoxanthine and inhibits the production of uric acid: used to treat gout …   English World dictionary

  • Allopurinol — Not to be confused with Enalapril. Allopurinol Systematic (IUPAC) name …   Wikipedia

  • Allopurinol — Strukturformel Allgemeines Freiname Allopurinol Andere Namen …   Deutsch Wikipedia

  • allopurinol — /al euh pyoor euh nawl , nol /, n. Pharm. a substance, C5H4N4O, used primarily in the treatment of chronic gout to decrease the synthesis of uric acid. [1960 65; appar. ALLO + PURINE + OL1] * * * ▪ chemical compound       drug used in the… …   Universalium

  • Allopurinol — Al|lo|pu|ri|nol [↑ allo (1), ↑ Purin u. ↑ ol (1)]; das; s: Freiname für einen als Hemmstoff der ↑ Xanthin Oxidase u. als ↑ Urikostatikum bei Gicht eingesetzten Purin Antimetaboliten. * * * Allopurinol …   Universal-Lexikon

  • allopurinol — noun Etymology: all + purine + 1 ol Date: 1964 a drug C5H4N4O used to promote excretion of uric acid …   New Collegiate Dictionary

  • allopurinol — (= 4 hydroxypyrazolo (3,4 d) pyrimidine) A xanthine oxidase inhibitor used in the treatment of gout …   Dictionary of molecular biology

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