hypothalamic-pituitary-adrenal axis
- hypothalamic-pituitary-adrenal axis
- the interrelationships between the endocrine structures and functions of the hypothalamus and adenohypophysis (the hypothalamic-pituitary axis) and the adrenal cortex, including production of corticotropin, its reception at sites in the adrenal cortex, and negative feedback mechanisms by which high levels of circulating glucocorticoids such as cortisol act on the hypothalamus and adenohypophysis to inhibit secretion of corticotropin. Called also HPA a. and hypothalamus-pituitary-adrenal a.
Medical dictionary.
2011.
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