microcytotoxicity assay

microcytotoxicity assay
the standard method of typing serologically defined human leukocyte antigens (HLA) as HLA-A, -B, and -C antigens. Multiple typing sera are placed in wells of a microtiter plate, and peripheral blood lymphocytes and complement are added to each well. The pattern of lysed cells indicates the HLA phenotype.

Medical dictionary. 2011.

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Look at other dictionaries:

  • microcytotoxicity test — mi·cro·cy·to·tox·ic·i·ty test .sīt ō .täk sis ət ē n a procedure using microscopic quantities of materials (as complement and lymphocytes in cell mediated immunity) to determine cytotoxicity (as to cancer cells or cells of transplanted tissue)… …   Medical dictionary

  • HLA typing — determination of the human leukocyte antigens (HLA) possessed by an individual. Class I antigens (HLA A, B, and C) are detected by lymphocyte microcytotoxicity assay using standard typing sera. Class II antigens are detected by one way mixed… …   Medical dictionary

  • Paul Terasaki — Born September 10, 1929 (1929 09 10) (age 82) Los Angeles, California Alma mater UCLA …   Wikipedia

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