- EAC rosette assay
- an assay for human B lymphocytes using complement receptors, a B cell marker. Peripheral blood cells are mixed with ox red blood cells, IgM antierythrocyte antibody, and complement deficient in C5 (to prevent red cell lysis). The antibody-and-complement-coated erythrocytes (EAC) form rosettes with B cells, which are counted using a hemocytometer.
Medical dictionary. 2011.