tumor-associated antigen

tumor-associated antigen
(TAA) an antigen that is associated with tumor cells; it may also be found under other conditions, as on normal cells during fetal life (oncofetal antigen) or on normal adult cells specific to certain organs (organ-specific antigen), or may occur normally on many cells but at a lower level.

Tumor-associated antigen used to detect micrometastases. Cytokeratins are expressed as tumor-associated antigens in some malignancies; cells from a lymph node draining a tumor site were stained by immunoalkaline phosphatase using a monoclonal antibody against a cytokeratin; the positive result, staining pink, indicates a carcinoma cell expressing cytokeratin.


Medical dictionary. 2011.

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