histocompatibility antigens

histocompatibility antigens
systems of allelic alloantigens that can stimulate an immune response that leads to transplant rejection when the donor and recipient are mismatched. Called also transplantation a's. See human leukocyte a's.

Medical dictionary. 2011.

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  • histocompatibility antigens major — the antigens in the major histocompatibility complex; HLA antigens in humans and H 2 antigens in mice …   Medical dictionary

  • histocompatibility antigens minor — systems of allelic alloantigens that can cause transplant rejection, but with a long delay (up to 100 days); about 15–30 such systems have been found in mice …   Medical dictionary

  • histocompatibility antigen — A set of plasmalemmal glycoproteins that are crucial for T cell recognition of antigens. Particularly the HLA system in humans and the H2 system in mice. There are two classes of histocompatibility antigens: (1) Class I; histocompatibility… …   Dictionary of molecular biology

  • histocompatibility — If tissues of two organisms are histocompatible, then grafts between the organisms will not be rejected. If, however, major histocompatibility antigens are different then an immune response will be mounted against the foreign tissue …   Dictionary of molecular biology

  • Histocompatibility — is the property of having the same, or mostly the same, alleles of a set of genes called the major histocompatibility complex. These genes are expressed in most tissues as antigens, to which the immune system makes antibodies. The immune system… …   Wikipedia

  • histocompatibility — A state of immunologic similarity (or identity) that permits successful homograft transplantation. * * * his·to·com·pat·i·bil·i·ty his (.)tō kəm .pat ə bil ət ē n, pl ties often attrib a state of mutual tolerance between tissues that allows them… …   Medical dictionary

  • histocompatibility antigen — noun any of the human leukocyte antigens (HLAs) which are the determinants of histocompatibility …   Wiktionary

  • histocompatibility — n. the form of compatibility that depends upon tissue components, mainly specific glycoprotein antigens in cell membranes. A high degree of histocompatibility is necessary for a tissue graft or organ transplant to be successful. Derivatives:… …   The new mediacal dictionary

  • Minor histocompatibility antigen — are receptors on the cell surface of donated organs that are known to give an immunological response in some organ transplants[1]. They cause problems of rejection less frequently than those of the major histocompatibility complex (MHC). Minor… …   Wikipedia

  • History and naming of human leukocyte antigens — In these instances, the A1/A2, A2/A3, A1/A3 are matched, decreasing the probability of a rejection because many are linked to a given haplotype. Occasionally the recombinant A1 Cw7 B7(rare), B7 becomes the alloantigen in a recipient with A1 Cw7… …   Wikipedia

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