monoclonal antibodies

monoclonal antibodies
chemically and immunologically homogeneous antibodies produced by hybridomas, used as laboratory reagents in radioimmunoassays, ELISA, and immunofluorescence assays; also used experimentally in cancer immunotherapy.

Monoclonal antibody production. HAT, HAT medium; PEG, polyethylene glycol.


Medical dictionary. 2011.

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  • Monoclonal antibodies — A general representation of the methods used to produce monoclonal antibodies. Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique… …   Wikipedia

  • monoclonal antibodies — Antibody An ti*bod y ([a^]n t[i^]*b[o^]d [y^]), n. 1. (Med., Physiol. Chem.) Any of various bodies or substances in the blood which act in antagonism to harmful foreign bodies, as toxins or the bacteria producing the toxins. Normal blood serum… …   The Collaborative International Dictionary of English

  • Nomenclature of monoclonal antibodies — List of stems for monoclonal antibody nomenclature[1][2][3] …   Wikipedia

  • List of monoclonal antibodies — This is a list of monoclonal antibodies, antibodies which are clones of a single parent cell. When used as medications, the generic names end in mab (see Nomenclature of monoclonal antibodies ) …   Wikipedia

  • Monoclonal — cells are defined as a group of cells produced from a single ancestral cell by repeated cellular replication. Thus they can be said to form a single clone .[1] The process of replication can occur in vivo, or may be stimulated in vitro for… …   Wikipedia

  • Monoclonal antibody therapy — Each antibody binds only one specific antigen. Monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically bind to target cells or proteins. This may then stimulate the patient s immune system to attack those cells.… …   Wikipedia

  • monoclonal antibody — Biotech. antibody produced by a laboratory grown cell clone, either of a hybridoma or a virus transformed lymphocyte, that is more abundant and uniform than natural antibody and is able to bind specifically to a single site on almost any chosen… …   Universalium

  • Monoclonal antibody — An antibody produced by a single clone of cells (specifically, a single clone of hybridoma cells) and therefore a single pure homogeneous type of antibody. Monoclonal antibodies can be made in large amounts in the laboratory and are a cornerstone …   Medical dictionary

  • monoclonal antibody — an antibody produced artificially from a cell clone and therefore consisting of a single type of immunoglobulin. Monoclonal antibodies are produced by fusing antibody forming lymphocytes from mouse spleen with mouse myeloma cells. The resulting… …   The new mediacal dictionary

  • monoclonal antibody — A type of protein made in the laboratory that can locate and bind to substances in the body and on the surface of cancer cells. There are many kinds of monoclonal antibodies; each one is made to find a different substance. Monoclonal antibodies… …   English dictionary of cancer terms

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