Pelger-Huлt anomaly

Pelger-Huлt anomaly
a benign autosomal dominant defect of neutrophils and eosinophils caused by mutations in the LBR gene (locus: 1q42.1), which encodes the lamin B receptor, in which their nuclei are bilobed or dumbbell-shaped and have a coarse and lumpy structure.

Medical dictionary. 2011.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Pelger-Huлt anomaly — Pel·ger Hu·Ð»t anomaly (pelґgər huґət) [Karel Pelger, Dutch physician, 1885–1931; G.J. Huлt, Dutch physician, 1879–1970] see under anomaly …   Medical dictionary

  • pseudo–Pelger-Huлt anomaly — an acquired condition clinically similar to Pelger Huлt anomaly, occurring in myelodysplastic syndrome and some leukemias; it is also seen occasionally as a reversible effect of drug toxicity …   Medical dictionary

  • acquired Pelger-Huлt anomaly — pseudo–Pelger Huлt a …   Medical dictionary

  • Pelger nuclear anomaly — Pelger nuclear anomaly. См. ядерная аномалия Пельгера. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Pelger-Huet anomaly — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 29515 ICD10 = ICD10|D|72|0|d|70 ICD9 = ICD9|288.2 ICDO = OMIM = 169400 MedlinePlus = eMedicineSubj = ped eMedicineTopic = 1753 MeshID = D010381Pelger Huet anomaly is a blood laminopathy… …   Wikipedia

  • Anomaly — A deviation from the usual, something different, peculiar, or abnormal. A congenital anomaly is something that is unusual and different at birth. A minor anomaly in this context is defined as an unusual anatomic feature that is of no serious… …   Medical dictionary

  • Pelger — Karel, Dutch physician, 1885–1931. See P. Huët nuclear anomaly …   Medical dictionary

  • May-Hegglin anomaly — Classification and external resources ICD 10 D72.0 …   Wikipedia

  • Reticular pigmented anomaly of the flexures — Classification and external resources OMIM 179850 Reticular pigmented anomaly of the flexures (also known as Dark dot disease, and Dowling–Degos disease ) is a reticular pigmented anomaly of the flexures, an autosomal dominant pigmentary disorder …   Wikipedia

  • Huët — G.J., Dutch physician, *1879. See Pelger H. nuclear anomaly …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”