an·nex·in (ə-nekґsin) any of a family of Ca2+-dependent phospholipid-binding proteins, which share a common primary structure in the C-terminal region, four or eight repeats of an approximately 70 amino acid sequence. Proposed functions include roles in mediation of intracellular calcium signals, aggregation of membranes and vesicles, and ion channel formation. Some inhibit activation of phospholipase A2, thus also inhibiting synthesis of prostaglandins and other arachidonic acid derivatives.

Medical dictionary. 2011.

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  • Annexin A5 — (or annexin V) is a cellular protein in the annexin group. The function of the protein is unknown, however annexin A5 has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with… …   Wikipedia

  • Annexin A1 — (or Lipocortin I) is a human protein encoded by the ANXA1 gene. PBB Summary section title = summary text = Annexin I belongs to a family of Ca(2+) dependent phospholipid binding proteins that have a molecular weight of approximately 35,000 to… …   Wikipedia

  • Annexin A2 — is a pleiotropic protein, meaning that its function is dependent on place and time in the body. PBB Summary section title = summary text = This gene encodes a member of the annexin family. Members of this calcium dependent phospholipid binding… …   Wikipedia

  • Annexin A3 — Annexin A3, also known as ANXA3, is a human gene.cite web | title = Entrez Gene: ANXA3 annexin A3| url = Cmd=ShowDetailView TermToSearch=306| accessdate = ] PBB Summary section title = summary text …   Wikipedia

  • Annexin V — is the cause of a syndrome called the antiphospholipid antibody syndrome with abnormal blood clotting. The annexins are a family of proteins first described in 1990. All of the annexin proteins share the property of binding calcium and… …   Medical dictionary

  • Annexin 2 — is a protein shown to be involved in diverse cellular processes such as cell motility (especially that of the epithelial cells), linkage of membrane associated protein complexes to the actin cytoskeleton, endocytosis, fibrinolysis, ion channel… …   Wikipedia

  • Annexin — Pfam box Symbol = Annexin Name = width = 220 caption = Structure of human annexin III. Pfam= PF00191 InterPro= IPR001464 SMART= PROSITE= PDOC00195 SCOP = 2ran TCDB = 1.A.31 OPM family= 43 OPM protein= 1w3w PDB=PDB3|1n00A:14 79 PDB3|1dk5B:15 80… …   Wikipedia

  • Annexin II — Structure cristallographique modélisée de l annexine II Annexine II (autres noms : Annexin II, Annexin A2, Annexin 2, Lipocortin II, Calpactin I heavy chain, Chromobindin 8, p. 36, Placental anticoagulant protein IV). UniProtKB/Swiss… …   Wikipédia en Français

  • Annexin A5 affinity assay — Annexin A5 is a protein that binds in a calcium dependent manner to phosphatidylserine containing membrane surfaces. Cell surface expression of phosphatidylserine during cell deathApoptosis is a form of programmed cell death which is used by the… …   Wikipedia

  • annexin — noun Any of a group of cellular proteins found in all kingdoms (animal, plant and fungi) with the exception of the bacteria …   Wiktionary

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