amino-acid N-acetyltransferase

amino-acid N-acetyltransferase
ami·no-ac·id N-ac·e·tyl·trans·fer·ase (ə-meґno asґid as″ə-tēl-transґfər-ās) [EC] an enzyme of the transferase class that catalyzes the transfer of an acetyl group from acetyl coenzyme A to the N-terminus of glutamate to form N-acetylglutamate. It can also act on aspartate and, slowly, on some other amino acids. Deficiency of the enzyme causes an aminoacidopathy with hyperammonemia but no oroticaciduria, similar to that seen in carbamoyl phosphate synthetase deficiency. Called also N-acetylglutamate synthetase.

Medical dictionary. 2011.

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