aldosterone synthase

aldosterone synthase
al·dos·ter·one syn·thase (al-dosґtər-ōn sinґthās) an isozyme of steroid 11β-monooxygenase that catalyzes the last three steps (11-hydroxylation, 18-hydroxylation, and 18-oxidation) in the synthesis of aldosterone from deoxycorticosterone. It includes the activities of steroid 11β-monooxygenase [EC 1.14.15.4] and corticosterone 18-monooxygenase [EC 1.14.15.5].

Medical dictionary. 2011.

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  • Aldosterone synthase — (or 18 hydroxylase) is a steroid hydroxylase cytochrome P450 oxidase enzyme involved in the generation of aldosterone. PBB Summary section title = summary text = This gene encodes a member of the cytochrome P450 superfamily of enzymes. The… …   Wikipedia

  • aldosterone synthase deficiency — al·dos·ter·one syn·thase de·fi·cien·cy (al dosґtər ōn sinґthās) a disorder of steroidogenesis caused by mutations in the CYP11B2 gene (locus: 8q21) that result in a deficiency of aldosterone synthase activity, impairing the… …   Medical dictionary

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  • Citrate synthase — Identifiers Symbol CS Entrez 1431 HUGO …   Wikipedia

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  • Steroid 11-beta-hydroxylase — Cytochrome P450, family 11, subfamily B, polypeptide 1 Identifiers Symbols CYP11B1; CPN1; CYP11B; DKFZp686B05283; FHI; FLJ36771; P450C11 External IDs …   Wikipedia

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