Medical dictionary. 2011.
Allosteric regulation — In biochemistry, allosteric regulation is the regulation of an enzyme or other protein by binding an effector molecule at the protein s allosteric site (that is, a site other than the protein s active site). Effectors that enhance the protein s… … Wikipedia
allosteric control — Inhibition or activation of an enzyme by a small regulatory molecule that interacts with the enzyme at a site (allosteric site) other than the active site (at which catalytic activity occurs). The interaction changes the shape of the enzyme, thus … Universalium
allosteric enzyme — (al o ster ik) An enzyme whose activity is altered by the binding of a small effector or modulator molecule at a regulatory site separate from the catalytic site; effector binding causes a conformational change in the enzyme and its catalytic… … Dictionary of microbiology
Negative allosteric modulator — A negative allosteric modulator (NAM) is a drug which decreases the activity of a receptor indirectly via disactivation of an allosteric site on the protein. NAMs are similar to inverse agonists in that they conteract overall receptor activation … Wikipedia
protein — proteinaceous /proh tee nay sheuhs, tee i nay /, proteinic, proteinous, adj. /proh teen, tee in/, n. 1. Biochem. any of numerous, highly varied organic molecules constituting a large portion of the mass of every life form and necessary in the… … Universalium
Glycogen phosphorylase — Phosphorylase The crystal structure of the rabit muscle glycogen phosphorylase AMP complex. AMP allosteric site (yellow), phosporylated Ser14 (orange), glycogen binding site (blue), catalytic site (red).[1] … Wikipedia
Antithrombin — Serpin peptidase inhibitor, clade C (antithrombin), member 1 Antithrombin monomer drawn from PDB 2ANT … Wikipedia
AMP-activated protein kinase — 5 AMP activated protein kinase or AMPK consists of three proteins (subunits) that together make a functional enzyme, conserved from yeast to humans, that plays a role in cellular energy homeostasis. It is expressed in a number of tissues,… … Wikipedia
cGMP-specific phosphodiesterase type 5 — Phosphodiesterase 5A, cGMP specific PDB rendering based on 3BJC … Wikipedia
CGMP specific phosphodiesterase type 5 — is an enzyme (EC number|3.1.4.17) from the phosphodiesterase class. It is found in various tissues, most prominently the corpus cavernosum and the retina.The phosphodiesterase (PDE) isozymes, found in several tissues including the rod and cone… … Wikipedia
