tacrolimus

tacrolimus
n.
a powerful immunosuppressant administered orally or by intravenous infusion to prevent rejection of transplanted organs. It is now also, in the form of an ointment, the first effective noncorticosteroid treatment for atopic eczema. Side-effects include gastrointestinal disturbances, tremor, headache, and kidney impairment. Trade name: Prograf.

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tac·ro·li·mus (tak″ro-liґməs) a macrolide immunosuppressant of the calcineurin inhibitor group, derived from Streptomyces tsukubaensis and having actions similar to those of cyclosporine. Administered orally or intravenously to prevent rejection of organ transplants, especially liver; applied topically to treat moderate to severe atopic dermatitis.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Tacrolimus — Nombre (IUPAC) sistemático …   Wikipedia Español

  • Tacrolimus — Général Nom IUPAC …   Wikipédia en Français

  • tacrolimus — agente inmunosupresor, macrólido obtenido del Streptomyces tsukubaensis. Posee una actividad similar pero más potente que la ciclosporina, inhibiendo las respuestas inmunológicas celulares y humorales. En modelos animales de transplantes, el… …   Diccionario médico

  • tacrolimus — /tə krōˈli məs/ noun A drug used in the treatment of atopic eczema and to prevent the rejection of organs after transplantation …   Useful english dictionary

  • Tacrolimus — Strukturformel Allgemeines Freiname Tacrolimus …   Deutsch Wikipedia

  • Tacrolimus — drugbox IUPAC name = 3S [3R* [E(1S*,3S*,4S*)] ,4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*] 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a hexadecahydro 5, 19 dihydroxy 3 [2 (4 hydroxy 3 methoxycyclohexyl) 1 methylethenyl] 14,16 dimethoxy 4 …   Wikipedia

  • Tacrolimus — Химическая структура молекулы Такролимуса Такролимус (Tacrolimus) иммуносупрессивный препарат, относящийся к группе природных макролидов. Продуцируется актиномицетом Streptomyces tsukubaensis. Открыт в 1987 году в Японии группой T. Goto, T. Kino… …   Википедия

  • tacrolimus — noun An immunosuppressive drug used mainly after organ transplantation. Syn: fujimycin, FK 506 …   Wiktionary

  • tacrolimus — n. a powerful immunosuppressant administered orally or by intravenous infusion to prevent rejection of transplanted organs. Side effects include gastrointestinal disturbances, tremor, headache, and liver and kidney impairment; it may have adverse …   The new mediacal dictionary

  • tacrolimus — A drug used to help reduce the risk of rejection by the body of organ and bone marrow transplants …   English dictionary of cancer terms

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