freeze drying

freeze drying
a method for the fixation of histological specimens, involving a minimum of chemical and physical change. Specimens are immersed in isopentane cooled to -190°C in liquid air. This fixes the tissue instantly, without the formation of large ice crystals (which would cause structural changes). The tissue is then dehydrated in a vacuum for about 72 hours at -32.5°C.

Medical dictionary. 2011.

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  • Freeze drying — (also known as lyophilization or cryodesiccation) is a dehydration process typically used to preserve a perishable material or make the material more convenient for transport. Freeze drying works by freezing the material and then reducing the… …   Wikipedia

  • Freeze-drying — Freeze dry Freeze dry (fr[=e]z dr[imac] ), v. t. [imp. & p. p. {Freeze dried}; p. pr. & vb. n. {Freeze drying}.] to remove the moisture from (e.g. food) by first freezing and then subjecting to a high vacuum; used as a mild method for drying… …   The Collaborative International Dictionary of English

  • freeze-drying — freeze drying. См. лиофилизация. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • freeze drying — sublimacinis džiovinimas statusas T sritis chemija apibrėžtis Drėgmės ar tirpiklio likučių šalinimas vakuumuojant užšaldytą medžiagą. atitikmenys: angl. freeze drying; freeze drying; lyophilic drying; lyophilization; sublimation drying rus.… …   Chemijos terminų aiškinamasis žodynas

  • freeze-drying — sublimacinis džiovinimas statusas T sritis chemija apibrėžtis Drėgmės ar tirpiklio likučių šalinimas vakuumuojant užšaldytą medžiagą. atitikmenys: angl. freeze drying; freeze drying; lyophilic drying; lyophilization; sublimation drying rus.… …   Chemijos terminų aiškinamasis žodynas

  • freeze-drying — sublimacinis džiovinimas statusas T sritis Energetika apibrėžtis Užšaldytų biologinės kilmės medžiagų džiovinimas vakuume. Taip džiovinamų medžiagų nesuardoma struktūra, užšaldytas galima ilgai laikyti, sudrėkintos jos atgauna pradines savybes ir …   Aiškinamasis šiluminės ir branduolinės technikos terminų žodynas

  • freeze-drying — noun a method of drying food or blood plasma or pharmaceuticals or tissue without destroying their physical structure; material is frozen and then warmed in a vacuum so that the ice sublimes • Syn: ↑lyophilization, ↑lyophilisation •… …   Useful english dictionary

  • freeze-drying — /freez druy ing/, n. a process for drying heat sensitive substances, as foods, blood plasma, antibiotics, and the like, by freezing the substance and then subliming the ice or other frozen solvent in a high vacuum. [1940 45] * * * …   Universalium

  • freeze drying — Method commonly adopted to produce a dry and stable form of biological material that has not been seriously denatured. By freezing the specimen, often with liquid nitrogen, and then subliming water from the specimen under vacuum, proteins are… …   Dictionary of molecular biology

  • freeze-drying — SYN: lyophilization. * * * freeze dry·ing (frēzґdri″ing) a method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. See also lyophilization …   Medical dictionary

  • freeze drying — dehydration in a vacuum from a frozen condition …   Dictionary of ichthyology

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