statin

statin
stat·in 'stat-ən n any of a group of drugs (as lovastatin and simvastatin) that inhibit the synthesis of cholesterol and promote the production of LDL-binding receptors in the liver resulting in a usu. marked decrease in the level of LDL and a modest increase in the level of HDL circulating in blood plasma

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n.
any one of a class of drugs that inhibit the action of hydroxymethylglutaryl coenzyme A reductase (HMG-CoA reductase), an enzyme that is involved in the liver's production of cholesterol. Statins can lower the levels of low-density lipoprotein (LDLs) by 25-45% and are used mainly to treat hypercholesterolaemia but also to reduce the risk of coronary heart disease in susceptible patients. Muscle inflammation and breakdown is a rare but serious side-effect of statins. The class includes atorvastatin, cerivastatin (Lipobay), fluvastatin (Lescol), pravastatin, and simvastatin.

Medical dictionary. 2011.

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  • statin — statín, ă, adj. (reg.; în sintagmă) măr statin = varietate de măr. Trimis de blaurb, 12.01.2007. Sursa: DAR …   Dicționar Român

  • statin — [stat′ n] n. any of a class of drugs, as lovastatin, that lower the levels of LDL and cholesterol in the blood, commonly used in treating heart disease * * * stat·in (stătʹn) n. Any of a class of lipid lowering drugs that reduce serum cholesterol …   Universalium

  • statin — [stat′ n] n. any of a class of drugs, as lovastatin, that lower the levels of LDL and cholesterol in the blood, commonly used in treating heart disease …   English World dictionary

  • Statin — This article is about the group of cholesterol lowering drugs. For the amino acid, see Statine. Lovastatin, a compound isolated from Aspergillus terreus, was the first statin to be marketed. Statins (or HMG CoA reductase inhibitors) are a class… …   Wikipedia

  • Statin — Als Statin wird im allgemeinen medizinischen Sprachgebrauch ein Arzneistoff bezeichnet, das der pharmakologischen Substanzklasse der 3 Hydroxy 3 Methylglutaryl Coenzym A Reduktase (HMG CoA Reduktase )Inhibitoren angehört. Da HMG CoA ein… …   Deutsch Wikipedia

  • Statin — Sta|tin [griech. statikós = stellend, zum Stehen bringend, hemmend; ↑ in (3)], das; s, e: 1) aus Pepstatin isolierte optisch aktive Hydroxyaminosäure, die eine spezif. Hemmwirkung auf bestimmte Proteasen ausübt; 2) Sammelbez. für bestimmte ↑… …   Universal-Lexikon

  • statin — UK [ˈstætɪn] / US noun [countable] Word forms statin : singular statin plural statins medical a drug that is used to reduce the amount of cholesterol in the blood …   English dictionary

  • statin — noun Etymology: from statin (as in lovastatin) Date: 1986 any of a group of drugs (as lovastatin and simvastatin) that inhibit the synthesis of cholesterol and promote the production of LDL binding receptors in the liver resulting in a usually… …   New Collegiate Dictionary

  • -statin — sta|tin [↑ Statin] 1) Grundwort in von der WHO empfohlenen Freinamen von ↑ Lipidsenkern, die die Biogenese des Cholesterins blockieren, indem sie die enzymatische Mevalonsäure Synthese hemmen, z. B. Lova , Simva , Prava , Fluvastatin; 2)… …   Universal-Lexikon

  • statin — Any of a group of drugs that lower the amount of cholesterol and certain fats in the blood. Statins inhibit a key enzyme that helps make cholesterol. Statin drugs are being studied in the prevention and treatment of cancer …   English dictionary of cancer terms

  • statin — noun a medicine that lowers blood cholesterol levels by inhibiting HMG CoA reductase • Syn: ↑lipid lowering medicine, ↑lipid lowering medication, ↑statin drug • Hypernyms: ↑medicine, ↑medication, ↑medicament, ↑ …   Useful english dictionary

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