radioreceptor assay

radioreceptor assay
ra·dio·re·cep·tor assay -ri-'sep-tər- n an assay for a substance and esp. a hormone in which a mixture of the test sample and a known amount of the radiolabeled substance under test is exposed to a measured quantity of receptors for the substance and the amount in the test sample is determined from the proportion of receptors occupied by radiolabeled molecules of the substance under the assumption that labeled and unlabeled molecules bind to the receptor sites at random

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a radioligand assay in which a radiolabeled hormone is used to measure the concentration of specific cellular receptors for the hormone in tissue specimens, an example being radioassay of estrogen receptors in breast tissue.

Medical dictionary. 2011.

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