Medical dictionary. 2011.
Polyketide — Als Polyketide bezeichnet man eine große Gruppe von Naturstoffen, die bezüglich ihrer chemischen Strukturen und pharmakologischen Eigenschaften äußerst heterogen zusammengesetzt ist. Gemeinsam ist ihnen die Biosynthese über den sogenannten… … Deutsch Wikipedia
Polyketide — Polyketides are secondary metabolites from bacteria, fungi, plants, and animals. Polyketides are biosynthesized by the polymerization of acetyl and propionyl subunits in a similar process to fatty acid synthesis (a Claisen condensation). cite… … Wikipedia
Polykétide — Polycétide Les polycétides [1] sont des métabolites secondaires de bactéries, champignons, végétaux et animaux qui proviennent de la condensation itérative de sous unités acétyle ou malonyle par des enzymes spécialisées les polycétides synthases… … Wikipédia en Français
Polyketide synthase — Polyketide synthases, also known as PKSs, are a family of enzymes or enzyme complexes that produce polyketides, a large class of secondary metabolites, in bacteria, fungi, plants, and animals. The biosyntheses of polyketides share striking… … Wikipedia
polyketide — noun Etymology: International Scientific Vocabulary poly + ket + ide Date: 1927 any of a large class of diverse compounds that are characterized by more than two carbonyl groups connected by single intervening carbon atoms, that are produced… … New Collegiate Dictionary
polyketide — noun a) Any polymer whose monomers is a ketide. b) Any of many biochemical intermediates, having such a structure, that occur in biosynthesis and metabolism. Syn: acetogenin … Wiktionary
griseofulvin — Polyketide antibiotic from Penicillium griseofulvum. Used therapeutically as an antifungal. Blocks microtubule assembly and thus mitosis … Dictionary of molecular biology
DEBS (6-deoxyerythronolide B synthase) — 6 Deoxyerythronolide B Synthase or DEBS has been identified as a Type 1 polyketide synthase. DEBS is found in Saccharopolyspora erythraea and responsible for the synthesis of the macrolide ring which is the precursor of the antibiotic… … Wikipedia
Biosynthesis of doxorubicin — Doxorubicin (DXR) is a 14 hydroxylated version of daunorubicin, the immediate precursor of DXR in its biosynthetic pathway. Daunorubicin is more abundantly found as a natural product because it is produced by a number of different wild type… … Wikipedia
Mycolactone — IUPAC name [(6S,7S,9E,12R) 12 [(E,2S,6R,7R,9R) 7,9 dihydroxy 4,6 dimethyldec 4 en 2 yl] 7,9 dimethyl 2 oxo 1 oxacyclodode … Wikipedia
