methicillin

methicillin
meth·i·cil·lin .meth-ə-'sil-ən n a semisynthetic penicillin C17H19N2O6NaS that is esp. effective against beta-lactamase producing staphylococci

* * *

n.
a semisynthetic penicillin that was originally used to treat infections by penicillin-resistant staphylococci. It has been superseded for this purpose by flucloxacillin but continues to be used to test the drug sensitivity of staphylococci. Methicillin-resistant staphylococci (MRS) can be responsible for increasing rates of infection in hospitals. Until recently, such infections have responded to vancomycin, but strains of bacilli have started to emerge that are resistant to both methicillin and vancomycin, giving rise to infections that are very difficult to treat. See also superinfection.

Medical dictionary. 2011.

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  • methicillin sodium — A semisynthetic penicillin salt for parenteral administration; restriction of its use to infections caused by penicillin G resistant staphylococci is recommended; it is less effective than penicillin G in infections caused by hemolytic… …   Medical dictionary

  • methicillin — noun Etymology: meth + penicillin Date: 1961 a semisynthetic penicillin C17H19N2O6NaS used especially in the form of its sodium salt against beta lactamase producing staphylococci …   New Collegiate Dictionary

  • methicillin — Penicillinase resistant penicillin antibiotic …   Dictionary of molecular biology

  • methicillin — /meth euh sil in/, n. Pharm. a semisynthetic penicillin antibiotic, C17H19N2NaO6S, used principally in the treatment of severe, penicillin resistant staphylococci infections. [1960 65; METH(YL) + (PEN)ICILLIN] * * * …   Universalium

  • methicillin — noun An antibiotic drug, chemically related to penicillin, often used against strains of bacteria which have become resistant to penicillin …   Wiktionary

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