methacholine

methacholine
metha·cho·line .meth-ə-'kō-.lēn n a parasympathomimetic drug administered in the form of its crystalline chloride C8H18ClNO2 esp. to diagnose hypersensitivity of the bronchial air passages (as in asthma) see MECHOLYL, provocholine

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meth·a·cho·line (meth″ə-koґlēn) a cholinergic agonist, having a longer duration of action than acetylcholine and predominantly muscarinic effects; it has vasodilator and cardiac vagomimetic effects but has largely been replaced by other drugs. It is also used in bronchial challenge testing.

Medical dictionary. 2011.

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  • Methacholine — Systematic (IUPAC) name 2 (acetyloxy) N,N,N trimethylpropan 1 aminium Clinical data AHFS/Drugs.com …   Wikipedia

  • Methacholine challenge test — A methacholine challenge test is a medical test used to assist in the diagnosis of asthma. The patient breathes in nebulized methacholine. This provokes narrowing of the airways (bronchoconstriction). This is detected when the patient performs… …   Wikipedia

  • methacholine chloride — A derivative of acetylcholine; a parasympatomimetic agent used as a bronchoconstrictor in testing for bronchial hyperreactivity. * * * [USP] the chloride salt of methacholine, used as a cholinergic, especially in the treatment of Raynaud disease …   Medical dictionary

  • methacholine challenge — a type of bronchial challenge or inhalational challenge used as a test for airway reactivity or atopic asthma; aerosolized methacholine is applied to the airways and the patient is assessed for responsiveness or hyperresponsiveness …   Medical dictionary

  • methacholine — noun A synthetic choline ester that alters the activity of muscarinic receptors in certain neurons …   Wiktionary

  • methacholine — metha·choline …   English syllables

  • methacholine — noun parasympathomimetic drug (trademark Mecholyl) that stimulates secretions and smooth muscle activity • Syn: ↑Mecholyl • Usage Domain: ↑trademark (for: ↑Mecholyl) • Hypernyms: ↑medicine, ↑ …   Useful english dictionary

  • MICR — methacholine inhalation challenge response …   Medical dictionary

  • MICR — • methacholine inhalation challenge response …   Dictionary of medical acronyms & abbreviations

  • Metacholintest — Der Methacholintest (Methacholin Provokationstest, engl.: Methacholine Challenge Test ) ist ein unspezifischer, inhalativer Provokationstest, der in der Pneumologie und Allergologie zur Messung von bronchialer Obstruktion und Hyperreaktivität… …   Deutsch Wikipedia

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