major basic protein

major basic protein
major basic protein n a toxic cationic protein that is the principal protein found in the granules of eosinophils and that is capable of damaging tissue (as of the eye) if released into extracellular spaces abbr. MBP

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(MBP) a cationic 10- to 15-kD protein occurring in eosinophilic granules and having cytotoxic activity against many parasites; it can also induce tissue injury in allergic and inflammatory diseases and, because it induces injury to the bronchial epithelium, is linked to asthma.

Medical dictionary. 2011.

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