Hodgkin's disease

Hodgkin's disease
Hodg·kin's disease 'häj-kənz- n a neoplastic disease that is characterized by progressive enlargement of lymph nodes, spleen, and liver and by progressive anemia
Hodgkin Thomas (1798-1866)
British physician. Hodgkin made important contributions in pathology, including a treatise on the anatomy of diseased tissue that spurred the study of tissue pathology in Great Britain. He is known for his description of aortic regurgitation in 1829 and of Hodgkin's disease in 1832. The latter disease was named in his honor in 1865 by fellow British physician Sir Samuel Wilks (1824-1911).

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a malignant disease of lymphatic tissue - a form of lymphoma - usually characterized by painless enlargement of one or more groups of lymph nodes in the neck, axillae (armpits), groin, chest, or abdomen; the spleen, liver, bone marrow, and bones may also be involved. Apart from the enlarging nodes, there may also be weight loss, fever, profuse sweating at night, and itching (known as B symptoms). Hodgkin's disease is distinguished from other forms of lymphoma by the presence of large binucleate cells (Sternberg-Reed cells) in the affected lymph nodes. Treatment depends on the extent of disease and may include surgery, radiotherapy, drug therapy, or a combination of these. Drugs used in the treatment of the disease include nitrogen mustard, vincristine, procarbazine, prednisolone, chlorambucil, and vinblastine. Many patients can be cured; in the early stages of the disease this may be in the order of 85% or more.
T. Hodgkin (1798-1866), British physician

Medical dictionary. 2011.

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Look at other dictionaries:

  • Hodgkin's disease — ► NOUN ▪ a malignant disease of lymphatic tissues typically causing enlargement of the lymph nodes, liver, and spleen. ORIGIN named after the English physician Thomas Hodgkin (1798 1866) …   English terms dictionary

  • Hodgkin's disease — [häj′kinz] n. [after Dr. T. Hodgkin (1798 1866), Eng physician who first described it] a chronic disease of unknown cause characterized by progressive enlargement of the lymph nodes and inflammation of other lymphoid tissues, esp. of the spleen …   English World dictionary

  • Hodgkin's disease — Hodg kin s dis*ease (Med.) A morbid condition characterized by progressive an[ae]mia and enlargement of the lymphatic glands; first described by Dr. Hodgkin, an English physician …   The Collaborative International Dictionary of English

  • Hodgkin's disease — 1877, named for Dr. Thomas Hodgkin (1798 1866) who first described it …   Etymology dictionary

  • Hodgkin's disease — a malignant disease of lymphatic tissue – a form of lymphoma – usually characterized by painless enlargement of one or more groups of lymph nodes in the neck, axillae (armpits), groin, chest, or abdomen; the spleen, liver, bone marrow, and bones… …   The new mediacal dictionary

  • Hodgkin's disease — noun Etymology: Thomas Hodgkin died 1866 English physician Date: 1865 a neoplastic disease that is characterized by progressive enlargement of lymph nodes, spleen, and liver and by progressive anemia called also Hodgkin s, Hodgkin s lymphoma …   New Collegiate Dictionary

  • Hodgkin's disease — /ˈhɒdʒkənz dəziz/ (say hojkuhnz duhzeez) noun a form of cancer involving the lymph glands whose symptoms sometimes include swellings, usually painless, of the lymph glands, especially those in the neck. Also, Hodgkin s lymphoma. {named after… …  

  • Hodgkin's disease —    Occasionally mispunctuated, as here: Two years later, he was found to be suffering from Hodgkins disease (Newsweek). The disease was first described by a British physician named Thomas Hodgkin …   Dictionary of troublesome word

  • Hodgkin's disease — noun a malignant disease of lymphatic tissues typically causing enlargement of the lymph nodes, liver, and spleen. Origin C19: named after the English physician Thomas Hodgkin …   English new terms dictionary

  • Hodgkin's disease — Hodg′kin s disease n. pat a malignant disorder characterized by enlargement of the lymph nodes and spleen and by lymphoid infiltration along the blood vessels • Etymology: 1860–65; after Thomas Hodgkin (1798–1866), London physician who described… …   From formal English to slang

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