antilymphocyte serum

antilymphocyte serum
antilymphocyte serum n a serum containing antibodies against lymphocytes that is used for suppressing graft rejection caused by lymphocyte-controlled immune responses in organ or tissue transplant recipients

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an antiserum, containing antibodies that suppress lymphocytic activity, prepared by injecting an animal with lymphocytes. ALS may be given to a patient to prevent the immune reaction that causes tissue rejection following transplantation of such organs as kidneys or of bone marrow. Administration naturally also impairs other immunity mechanisms, making infection a serious hazard.

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(ALS) antiserum derived from animals that have been immunized against human lymphocytes, a powerful nonspecific immunosuppressive agent that causes destruction of circulating lymphocytes.

Medical dictionary. 2011.

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  • antilymphocyte serum — ˌ… noun : a serum containing antibodies against lymphocytes that is used for suppressing graft rejection caused by lymphocyte controlled immune responses in organ or tissue transplant recipients * * * antilymphocyte serum /an ti limˈfə sīt… …   Useful english dictionary

  • antilymphocyte serum — antilymphocyte globulin; = ALS; = ALG an antiserum, containing antibodies that suppress lymphocytic activity, prepared by injecting an animal with lymphocytes. ALS may be given to a patient to prevent the immune reaction that causes tissue… …   The new mediacal dictionary

  • antilymphocyte serum — Immunoglobulins raised xenogeneically against lymphocyte populations. Referring particularly to antisera recognizing one or more antigenic determinants on T cell populations. Of use in experimental immunosuppression …   Dictionary of molecular biology

  • antilymphocyte globulin — antilymphocyte serum …   The new mediacal dictionary

  • antilymphocyte globulin — an·ti·lym·pho·cyte globulin .lim(p) fə .sīt n serum globulin containing antibodies against lymphocytes that is used similarly to antilymphocyte serum * * * (ALG) the gamma globulin fraction of antilymphocyte serum (q.v.), used as an… …   Medical dictionary

  • antilymphocyte globulin — ˌ… noun Etymology: anti (I) + lymphocyte : serum globulin containing antibodies against lymphocytes that is used similarly to antilymphocyte serum …   Useful english dictionary

  • antilymphocyte-globulin — see antilymphocyte serum …   Medical dictionary

  • Сыворотка Антилимфоцитарная (Antilymphocyte Serum, Als), Глобулин Антилимфоцитарный (Antilymphocyte Globulin, Alg) — иммунная сыворотка, в состав которой входят антитела, подавляющие лимфоцитарную активность; изготавливается из лимфоцитов животных. Антилимфоцитарная сыворотка может вводиться больному для предотвращения иммунной реакции, вызывающей отторжение… …   Медицинские термины

  • Serum — The clear liquid that can be separated from clotted blood. Serum differs from plasma, the liquid portion of normal unclotted blood containing the red and white cells and platelets. It is the clot that makes the difference between serum and plasma …   Medical dictionary

  • antilymphocytic serum — n ANTILYMPHOCYTE SERUM …   Medical dictionary

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