Z-DNA

Z-DNA
zig-zag (left-handed helical) deoxyribonucleic acid

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Z-DNA 'zē- n the left-handed uncommon form of double helix DNA in which the chains twist up and to the left around the front of the axis of the helix and which has 12 base pairs in each helical turn and one groove on the external surface compare B-DNA

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a double helical structure assumed by double-stranded DNA, in which the phosphate groups form a dinucleotide repeating unit zigzagging up a left-handed helix with a single, deep groove; it is particularly likely to occur in stretches of alternating purines and pyrimidines or under dehydrating conditions. Cf. A-DNA and B-DNA.

Medical dictionary. 2011.

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